41 In a more recent meta-analysis, there were no differences between operative and nonoperative approaches in short-term functional outcomes at 6 months, and there were increased complications in patients treated surgically
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North America accounted for the second-largest market in 2022, it is projected to grow at a CAGR
[16] Although cyanocobalamin lacks a defined upper-toxicity threshold due to its water solubility and renal elimination, exceptionally high cumulative doses have been temporally associated with acneiform eruptions, altered potassium homeostasis, and theoretical thrombotic risk, emphasizing the importance of evidence-based dosing
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