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To address the role of NPY in COPD, studies utilizing antagonists or agonists in animal models or humans with COPD are required

Finally, weight loss, even with the aid of GLP-1 medications, can be more challenging in a hormone-deficient state, including late perimenopause, menopause, and the postmenopausal years

Jahadi M, Khosravi-Darani K, Ehsani MR, Mozafari MR, Saboury AA, Pourhosseini PS

doi: 10.1001/jamainternmed.2013.2720 83 WaserBBlankAKaramitopoulouEPerrenAReubiJC

Women experience this effect more strongly than men, which means that even with consistent GLP-1 therapy, weight loss can slow or stop temporarily

PMID 25820384