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Blockages within the choroidal blood vessels, possibly due to vascular disease, lead to increased ocular rigidity and decreased efficiency in the choroidal blood circulation system

After 72 h, the resulting solution was freeze-dried by using low-temperature freeze dryers, yielding P1(1.23 g) as a yellow powder

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Both are dominated by gastrointestinal adverse events nausea, constipation, diarrhea, vomiting that are mostly mild-to-moderate and dose-related

Risk bias assessments were conducted independently by two reviewers

Retrograde menstruation in healthy women and in patients with endometriosis