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Furthermore, using a murine cholangitis model, the researchers clarified the underlying mechanisms: butyrate activates peroxisome proliferator-activated receptor delta (PPARD) to promote fatty acid -oxidation (FAO)-mediated metabolic reprogramming

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Hirbe AC, Pekmezci M, Dahiya S, Apicelli AJ, Van Tine BA, Perry A, et al

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Figure 10 demonstrates the ability of Axcess excipients to inhibit the activity of both trypsin and chymotrypsin, using fluorogenic substrates to monitor the degradation of these peptides to release fluorescent breakdown products