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Dena Dubals lab at UCSF (Cell Reports, 2017) showed that peripheral klotho fragment administration enhanced cognition and neural resilience in young, aging, and -synuclein transgenic mice through NMDA receptor-dependent mechanisms

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Results Peroral d-allulose suppresses food intake without aversion Peroral (p.o.) administration of d-allulose (Allu) at 1 and 3 g kg 1 , but not 0.3 g kg 1 , into the stomach using a stainless feeding needle decreased cumulative food intake for 0.5, 1, 2, 3, and 6 h after injection in C57BL/6J mice fasted overnight (16 h) (Fig

Reducing these levels is a significant benefit for those suffering from AFS

By replenishing glutathione levels through supplementation, we may help mitigate some of the oxidative damage associated with aging