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M., Morales A., Blasco C., Colell A., Mari M., Garcia-Ruiz C., et al

Materials and Methods Experimental Animals and Groups In our study, we raised 120 specific pathogen-free (SPF) grade Wistar male rats (180 20 g weight and 24 weeks old, which is equivalent to 1820 years old in humans) provided by the Experimental Animal Center of the 940th Hospital of Joint Logistics Support force of Chinese Peoples Liberation Army (licence: SCXY (Military) 20120020)

Rest: Allowing the body time to recover by getting adequate rest

Thus, in comparison with several oral antidiabetic drugs that are available for managing type II diabetes mellitus, including metformin, sulfonylureas, sodiumglucose cotransporter 2 (SGLT2) inhibitors, thiazolidinediones, alphaglucosidase inhibitors, and meglitinides [138, 139], the benefits of DPP4 inhibitors relative to other oral antidiabetic medications are summarized in Table 3

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