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RA IFP was characterized by increased -alanine levels that were also reflected in the observed alterations in the pyrimidine metabolism pathway [20] and, according to AUC and VIP scores, -alanine emerged as a potential RA biomarker

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No.82102607)

This creates a translational gap

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The translational relevance of the present findings was supported by showing TRPA1 mRNA in human EWcp in both UCN1 and CART-immunoreactive neurons, furthermore, using ultrasensitive RNAscope ISH technique combined with immunofluorescence we provided evidence that in line with mice 3 , UCN1 and CART are co-localized in the human EWcp also