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However, habitual overeatingmultiple episodes per weekaccumulates excess calories that slow or halt weekly weight loss, frustrating patients and creating a false impression that semaglutide has stopped working

Mathiesen DS, et al

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To determine, firstly, whether mean metabolite component scores in patients with stable schizophrenia differ from mean scores in healthy controls, and secondly, whether this difference is significantly leveraged by the sub-group of patients with residual schizophrenia, we regressed each component score in turn on two participant variables using a hierarchical regression model

LCMS/MS was carried out on an UltiMate 3000 nanoLC coupled to a Q Exactive Plus Orbitrap (Thermo Fisher Scientific) using aqueous and acetonitrile mobile phases, each supplemented with 0.1% formic acid