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To the contrary, in one of our editorials, we even have provided a detailed list of 34 (and still counting) veterinary journal articles in which their cardiologists-authors concluded that there are significant breed-specific variations in echocardiographic indices measuring left chamber dimensions, when determining whether or not an MVD-affected dog's left atrium or left ventricle is, in fact, enlarged

Sharma P, Huq AU, Singh R

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Biological Trace Element Research, 201 (1), 121-128

Other important factors include: Duration of diabetes : Longer disease duration is associated with greater beta-cell dysfunction, which may reduce the incretin-based response to DPP-4 inhibition Residual beta-cell function : As DPP-4 inhibitors rely on stimulating endogenous insulin secretion, patients with significantly impaired beta-cell reserve may respond less well Adherence to treatment : Consistent daily dosing is essential

Laboratory Gloves Wearing gloves is standard practice