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Science 289(5482):11971202 Zhang L et al (2003) Tumor-derived vascular endothelial growth factor up-regulates angiopoietin-2 in host endothelium and destabilizes host vasculature, supporting angiogenesis in ovarian cancer

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Methods Materials LC/MS-grade methanol, acetonitrile and ammonium hydroxide were purchased from Kanto Chemical (Tokyo, Japan)