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The limited incorporation of advanced omics platforms, like metabolomics and metatranscriptomics has yet to reliably identify biomarkers of RT response and toxicity (Liu et al., 2021)

Also, in the presence of Fe2+ it is converted to deleterious hydroxyl radical (OH) through Fenton reaction

Urick said discontinuation can be attributed to five common causes, of which side effects are only one, along with affordability, availability, physician drug switches and the achievement of weight loss goals

Osna et al., 2022

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