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The results of cDNA expression profile analysis indicated that six genes, including GPX4 , GSS , KEAP1 , SQSTM1 , SLC7A11 , ATG3 , and ATG5 , were highly expressed in tumor tissues from patients with ovarian cancer (Figure 4A, 4B)

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Previously unreported effects of RSL3, such as degradation of mTOR signaling pathway protein, p70S6K, and reduction of p-NPM1 levels were identified in the present study and warrant further investigation