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This approval makes Eli Lillys oral GLP-1 receptor agonist, to be marketed as Foundayo, the second GLP-1 drug for weight loss available in pill form, after Wegovy, which gained approval in December 2025

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Its unique mechanism targets GLP-1 alongside glucagon receptor pathways, and studies examine its metabolic effects on energy expenditure, energy balance, glucose regulation, and gastric emptying

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DOI: 10.1186/s12986-016-0153-3, Kanoski, S

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pubmed.ncbi.nlm.nih.gov/37366315 UK regulatory status retatrutide is an unlicensed investigational compound supplied strictly for research, not human consumption, as of 2026.

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