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CCT-deficient B cells stimulated with LPS triggered early activation of the unfolded protein response (UPR)-mediated splicing of Xbp-1, and impaired class switching, reducing antigen-specific IgG1 production while increasing IgM secretion upon antigen challenge (104) ( Figure 3 )

J Natl Cancer Inst, 1993;85(19):1571-9

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To assess copper-dependent regulation of autophagy-related genes, the expression of six genes ( HSP90AA1 , GABARALP1 , UBC , PRAGC , PLOD2 , LAMTOR3 ) was measured in HepG2 and HepG2 ATP7B-KO cells after CuCl treatment

One potential advantage of febuxostat is that it is structurally quite different from allopurinol, and therefore likely can be used in patients who are allergic to allopurinol

Hold the vial horizontally between your palms and roll it back and forth