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The advantages of the iTIND include the ability to perform the procedure in-office under local anesthesia, without the need for a hospital stay or general anesthesia

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glucocorticoidGR complexes can also activate certain AR target genes leading to enzalutamide resistance Abstract Great strides have been made in the treatment of castration-resistant prostate cancer (CRPC) with the development of new antiandrogens (enzalutamide) and more potent androgen synthesis inhibitors (abiraterone) that have both improved patient outcomes

[DOI] [PMC free article] [PubMed] [Google Scholar] 17.Ohashi N., Kohno T

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