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Kim Y, Park IH, Shin J, Choi J, Jeon C, Jeon S, et al

The pattern of HFs in KTP mice has been observed in sheep and other animals [18], but not in normal mice

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A methodical rotation plan that leaves the same patch unused for 3 to 4 weeks, combined with technique adjustments like injecting over 5 to 10 seconds and holding the needle for 5 seconds, substantially reduces repeated-site irritation