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This deficiency may, in turn, contribute to dysregulated fatty acid metabolism and diminished mitochondrial energy productionmetabolic impairments frequently associated with fatigue in hypothyroid states

These approaches require medical procedures and carry higher costs and risks

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et al., 2023) the cAMP/PKA/p-CREB pathway was altered in the amygdala alongside neuronal apoptosis (Jiang et al., 2023), and cortical cytokinesincluding IL-1, IL-6, and TNF- were elevated (Wang J