these subjects were randomized to febuxostat 40 mg/day or allopurinol and were studied on further XOI dose titration, per protocol [23], to serum urate target of 5/year vs 8 versus HU 8 mg/dL (C), or presence of tophi (D)
When that happens, she explains, the goal isnt to stop treatment but to adjust it
if longer, skip and resume schedule Lifestyle considerations: Eat smaller meals to minimize GI effects Avoid fatty, greasy foods initially Stay hydrated No medication restrictions Comparison of Practicality Some patients prefer the simplicity of once-weekly dosing despite the injection
Pipeline Portfolio 8.1.11
Some medications that interact with grapefruit juice include statins (Atorvastatin), antihistamines (Fexofenadine), antihypertensives (Nifedipine), and antiarrhythmic drugs (Amiodarone) (6)
Is switching common in NZ now