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Since then, there has been an explosion of interest in these medications since they do work well

JAMA American Association of Clinical Endocrinology

Improved insulin sensitivity Studies have shown that the weight loss injection may enhance insulin sensitivity, making it easier for cells to respond to insulin and regulate blood sugar levels effectively

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This suggests OptumRx/United is willing to start high-efficacy GLP-1s under PA without forcing a semaglutide trial, but still only after low-cost alternatives

Reality: Injections are actually the most dangerous