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In DS mice, combination therapy, but not EMPA alone, completely inhibited the increase in sBP

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However, beyond weight gain, obesity involves a series of obesity-related diseases, which in patients with PWS can have a stronger impact, considering the early onset of obesity, the difficulties in adhering to lifestyle changes, use of psychotropic medications, and the inability to communicate some symptoms linked to mental retardation [24, 28]

British journal of pharmacology , 134 (8), 17051710

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