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Animals were raised at 24 2 C, 50%60% humidity, and 12-h/12-h lightdark cycle conditions, with four rats per cage

3, Oncogenic PI3K/AKT signaling stabilizes and activates nuclear factor erythroid 2related factor 2 (NRF2), a key regulator of antioxidant genes, driving upregulation of GSH biosynthetic enzymes

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Research on this compound has been limited primarily to laboratory and animal studies, with little to no human clinical trial data available

Our analysis aims to provide a theoretical foundation for the development of novel arrhythmia treatment strategies, while offering insights into future research directions for clinical application

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