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The first is extracellular matrix biology: fibroblast culture and rat wound-chamber work from the Maquart and Simeon groups reported that GHK-Cu stimulates collagen, glycosaminoglycan and small proteoglycan synthesis while simultaneously upregulating matrix metalloproteinase-2 and its tissue inhibitors, a combined synthesis-and-turnover signature unusual among matrix-active compounds

HGF stimulates hepatocyte mitogenesis, accelerates liver regeneration, and protects the liver from toxins

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