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Direct transcriptional targets of sex steroid hormones in bone

It also has benefits for sperm motility and potentially women's fertility: 4

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Tirzepatide, a novel agent belonging to the glucose-dependent insulinotropic peptide (GIP) and glucagon-like peptide-1 receptor agonist (GLP-1 RA) class (dual GIP/GLP-1 RA), has also been approved by the US Food and Drug Administration (FDA) and the European Medicines Agency (EMA) for the treatment of type 2 diabetes

These considerations argue for a more nuanced evaluation of centrally acting appetite peptides rather than categorical exclusion

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