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72 For example, the elimination rate constant of theophylline is less in cats (0.089/hr) 73 than dogs (0.12/hr), resulting in a longer half-life in the cat (7.8 hours) compared with the dog (5.7 hours), 64, 65 thus necessitating a smaller dose in cats

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The apparent discrepancy between the proportion of patients improving ED degree category measured by IIEF-6 questionnaire and vasculogenic ED degree category measured at dynamic PDU, might be probably justified by the different characteristics of the two methodologies

[1] It's important to note that missing a single dose occasionally is unlikely to cause serious harm for most patients, but your blood glucose levels may be less well controlled during this period