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The mechanism by which bacteria traverse the mucosal barrier remains unclear, with the most convincing studies suggesting that a specific transcytotic process involving specialized cells overlying the domes of intestinal lymphoid aggregates (Peyers patches) termed M-cells, which are characterized by a sparse glycocalyx, short and irregular microvilli and a microfold appearance [16, 17]

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195,196,197 UC patients usually have an imbalance in the abundance of beneficial bacteria and harmful bacteria in the intestinal microbiota, which affects the intestinal microenvironment and results in damage to intestinal epithelial cells and the intestinal barrier

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All other therapies were continued at their respective doses

Glutathione injections must be administered regularly to be effective