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In a published Phase 2 trial (48 weeks), adults with obesity who took retatrutide lost, on average, more weight at higher doses, with the 12 mg group showing 24.2% average weight change at 48 weeks (compared with 2.1% in the placebo group)

In the context of weight management, semaglutidea glucagon-like peptide-1 (GLP-1) receptor agonistis the active ingredient used in these formulations

(2024.) BMJ

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