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consider nutritional monitoring in long-term studies [9] Individual Variability: Response heterogeneity observed in clinical trials (some subjects non-responders) Research Compliance: Any research involving cagrilintide must be conducted in accordance with institutional review board (IRB) approval, Good Laboratory Practice (GLP) standards, and all applicable regulations

doi: 10.22034/mnba.2023.417415.1047 35 SharmeenJBMahomoodallyFMZenginGMaggiF

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The activity of ribosomal genes was evaluated through multiple cytogenetic indicators: the frequency of acrocentric chromosome associations, the number of nucleolar organizer regions (NORs) in these acrocentric chromosomes, and the intensity of silver staining (Ag-NOR staining)