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However, individuals with absorption disorders may require significantly higher doses to achieve therapeutic levels

Mol Endocrinol 1:243248 Rogers SA, Miller SB, Hammerman MR (1990) Growth hormone stimulates IGF I gene expression in isolated rat renal collecting duct

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Transgenic mice with overexpression of pituitary-specific Gpr101 develops gigantism phenotype and has hypersecretion of GH, in the absence of pituitary hyperplasia or tumorigenesis, thereby indicating that the role of Gpr101 in the pituitary enhances secretion rather than enhancing proliferation (437)

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