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Such oscillatory patterns are consistent with nonlinear decision pathways in routine care, in which therapy changes may reflect periodic reassessment, tolerability trade-offs, formulation preferences, or intermittent external constraints rather than a unidirectional escalation strategy [1, 18,19,20]
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According to the SmPC, these include: Nausea very common (may affect more than 1 in 10 people) Vomiting common (may affect up to 1 in 10 people) Abdominal pain and discomfort Diarrhoea or constipation Dyspepsia and reflux These symptoms can be particularly troublesome at night, especially if the evening meal is consumed close to bedtime
it is endowed with surfactant properties and is indispensable for the genesis of many enzymes and coenzymes, for the synthesis of ascorbic acid and nucleic acids