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Semaglutide, a GLP-1 receptor agonist approved by the FDA for type 2 diabetes and chronic weight management, can cause fatigue through several mechanisms

The above is usually talked of in terms of 'anaemia', but it does show that there is a complicated link between B12, B6, folic acid, zinc and vitamin D levels, chronic disease (anaemia of chronic disease) and how the body 'manages' serum iron, ferritin, and transferrin iron saturation and keeps these in balance (or not, as in your case)

A basic supplement stack of a multivitamin, omega-3 fatty acids, magnesium, and a probiotic can support overall health during rapid weight loss

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Distinguishing between normal adjustment fatigue and concerning tiredness that requires medical attention matters

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