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For starters, he says the lack of clinical data from human trials on many peptides means we dont know what benefits to expect, what dosages to use, or what the long-term risks or side effects could be

Khavinson VK, Izmaylov DM, Obukhova LK, Malinin VV (2000) Effect of epitalon on the lifespan increase in Drosophila melanogaster

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In one study, MOTS-c significantly enhanced physical performance and running time (approximately 12 percent to 15 percent increase) in mice of all ages, suggesting it can confer exercise benefits without physical activity