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Lira (GLP-1R) can reduce the occurrence of hepatic steatosis in vivo and in vitro by enhancing autophagy and lipid degradation through the GLP-1R-transcription factor EB (TFEB)-mediated autophagy lysosomal pathway [37]

doi: 10.1016/j.biopha.2019.109537 19 HelmstadterJ.FrenisK.FilippouK.GrillA.DibM.KalinovicS.et al

However, safe doesnt mean that there arent risks

2021;4(3) doi: 10.1001/jamanetworkopen.2021.1009

SGLT-2, sodium-glucose cotransporter-2

Shah says he would caution people with type 1 who are not overweight to avoid taking a GLP-1 drug, since retrospective studies have found that this group tends to have more gastrointestinal side effects, which may lead them to stop using the drug