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When to consider medication or a combined approach If you need substantial, rapid weight loss for metabolic health or have complex diabetes management, prescription GLP-1 receptor agonists like semaglutide (injectable) or tirzepatide (injectable) often produce larger and faster results in human clinical trials

Muscle protection: Supports weight reduction without the risk of losing muscle tissue (no catabolism)

"Efficacy and Safety of Semaglutide Once-weekly Versus Sitagliptin Once-daily as add-on to Metformin and/or TZD in Subjects With Type 2 Diabetes (SUSTAIN 2)"

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The fiber in plant foods also helps lower blood cholesterol levels to support overall heart health

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