Concurrent ICV administration of GLP- 1 and GIP significantly increased neuronal activation and pro-opiomelanocortin expression in the arcuate nucleus of the hypothalamus
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The result is an increased energy expenditure
Since oxidative stress may contribute to neurodegenerative disorders, there is strong research interest in epithalons role in optimizing sleep and maintaining overall brain health
For a 75 to 90kg adult, that translates roughly to 190 to 900mcg daily, which brackets the 200 to 500mcg range being used in practice
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