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Melasma can be managed and substantially reduced but often requires ongoing maintenance to prevent recurrence, because the hormonal and UV triggers that produced it remain present

If a patient receives a dosage significantly higher than advised, serious side effects like renal failure or blood poisoning may manifest

A change may be possible for some patients, but it should not be done without medical guidance

Injecting them within 60 minutes of a meal blunts growth hormone release by up to 80% (Nass et al., J Clin Endocrinol Metab, 2008)

Remember to consult your physician before you make changes to your diet during medically supervised weight loss

*Correspondence: Omar Dzaye [email protected] These authors share first authorship This article was submitted to Cardiovascular Therapeutics, a section of the journal Frontiers in Cardiovascular Medicine Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers