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2,8 While glutathiones antioxidant properties are well-documented, its topical formulations suffer from poor bioavailability

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confirmed that supplementation with n-3 PUFAs modify lipid composition in oocyte membranes, enhancing membrane fluidity and reducing susceptibility to lipid peroxidation ( in vitro maturation (IVM) ( 2 O 2 ) and MDA levels, which correlate with upregulated antiapoptotic and antioxidative gene expression ( 2.3 Epigenetically regulated metabolic pathways Epigenetically regulated metabolic pathways play a pivotal role in enhancing oocyte quality and developmental competence

however, there have been few in vivo and clinical trials

*Correspondence: Dongmei Shi, [email protected]