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Treatment with mizagliflozin resulted in robust improvement of glucose nadir, reduction of both peak glucose and insulin during the MMTT, and reduction in L3 and L2 events
If you stop eating abruptly and you go into a very caloric state, your bile gets sludgy
The conversation covers how our understanding of obesity as a chronic, relapsing disease has changed over the past 30 years, what the new clinical versus preclinical obesity framework means for how we diagnose and treat it, how GLP-1 drugs work and why they've succeeded where earlier medications failed, what the STEP and SELECT trials revealed about the disease-modifying potential of semaglutide, and how patients and clinicians should be thinking about who these drugs are really for
What sets retatrutide apart is its triple agonist approach, which means it acts on three hormone pathways in your body at the same time: GLP-1, GIP, and glucagon
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& Fu, Z
