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[DOI] [PMC free article] [PubMed] [Google Scholar] [23].Skov J, Dejgaard A, Frkir J, Holst JJ, Jonassen T, Rittig S, et al

Intracellularly, CHAC1 enzymatically degrades GSH into 5-oxoproline and Cys-Gly, acting as a pro-ferroptotic execution signal by accelerating GSH exhaustion 151

And right now we're relying on these two companies to produce the world's entire supply of these drugs

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Titin is an extremely large protein that is greater than 1 M in length and found in human striated muscle 22, 23