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Experimental data shows that the affinity of IGF-1 LR3 for IGF-1R is twice that of natural IGF-1, and its affinity for insulin receptor (IR) is reduced by 100 times, reducing the risk of hypoglycemia

Less Common But Important Semaglutide Side Effects Beyond gastrointestinal symptoms, some semaglutide users report fatigue, headache, dizziness, or muscle pain in the first 12 weeks of treatment

The price of GLP-1 RAs tends to be high compared with other medications for treating type 2 diabetes

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