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However, discontinuation of semaglutide in extension studies was associated with partial weight regain, underscoring the chronic nature of obesity and the likely need for ongoing pharmacotherapy to sustain benefits

10.1016/j.tips.2009.08.003 195 YoshidaT.AkahoshiF.SakashitaH.KitajimaH.NakamuraM.SondaS.et al (2012)

"It's going to be competitive," U.K

C-EL, BP and PU designed the study

The liraglutide plus exercise group retained the largest amount of weight loss a year after the conclusion of the intervention - retaining 6 kg more weight loss than the group on liraglutide alone

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