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Most available studies are limited by small sample sizes, short durations, and variability in study design, and importantly, they often include additional components alongside the three agents

Riboflavin role in migraine therapy is prophylactic, in other words, it affects migraine attacks frequency, severity, duration, and related disability, and facilitates acute therapies of migraine attacks (100)

Alemany S, Avella-Garca C, Liew Z, et al

Notch1 signaling promotes survival of leukemic cells in close contact with bone marrow-derived stromal cells by activating AKT and Stat-3 pathways

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