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This condition, like hereditary angioedema (HAE), results from dysregulation of the complement system

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according to Osteoarthritis Research Society International (OARSI) guidelines, non-steroidal anti-inflammatory drugs (NSAIDs) can only provide short-term symptom relief while carrying substantial risks of adverse gastrointestinal and cardiovascular events (Bannuru et al., 2019)

the case for making the diagnosis during the first week of life