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Brown, P., Pratt, A

I took this supplement for 30 days- 1 tablet in the morning and 2 tablets at bedtime

This is because berberine derivatives can cross the blood-brain barrier and target mitochondria in the meantime (Wang L

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Absorption problems Even with adequate intake, absorption can be reduced by: Certain gastrointestinal conditions affecting the stomach or small intestine Some medications Age-related reduction in stomach acid (which can affect absorption) Autoimmune gastritis (often historically referred to as pernicious anaemia) This is a well-recognised cause of B12 deficiency and may require ongoing management