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4.6% in the non-GLP-1 group Significantly lower rates of acute myocardial infarction Lower risk of major adverse cardiac events overall Psoriatic arthritis already raises cardiovascular risk substantially

The drug slows gastric emptying, which means that food moves more slowly from your stomach into your intestine

Combining them without guidance can be unsafe

While some studies suggest that GLP-1 is not the main cause of PBH [27, 28], others indicate that it has a critical role in symptomatic PBH [29]

For a peptide in aqueous solution, that uncertainty is not trivial

[1] [7] These findings are not directly comparable to results from trials of semaglutide or tirzepatide, as no head-to-head trials have been conducted