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Longer-term use (6+ months) may create more durable improvements where enhanced dermal architecture supports ongoing collagen synthesis at rates intermediate between treatment peaks and pre-treatment baseline, potentially maintaining 40-60% of peak improvements indefinitely without continuous peptide application

There is a growing body of evidence supporting the use of peptides in preventive health

Excessive DSIP dosing typically causes headaches, grogginess, or paradoxical insomnia rather than dangerous effects

Altered expression of KLC3 may affect semen parameters

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