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Ethacraplatin a dual-threat platinum (IV) prodrug is a cisplatin molecule coordinated to two ethacrynic acid ligands which is able to inhibit irreversibly GSTP1-1 enzymatic activity being reduced and cleaved as a consequence of binding (Fig

As tCho can be interpreted as a marker of tissue cellularity, this suggests that at 3 months lower tCho could indicate lower cellular density 31

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