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Consent for publication Not applicable in this review

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Additionally, patients taking insulin or sulfonylureas may have an increased risk of hypoglycaemia when starting Mounjaro and may need dose adjustments of these medications

Introduction Dizziness or lightheadedness can happen while taking semaglutide (Ozempic, Wegovy) or tirzepatide (Mounjaro, Zepbound)

Melanotan-1 (afamelanotide) is a selective MC1R agonist producing melanogenesis with minimal off-target effects, while Melanotan-2 binds MC1R, MC3R, and MC4R causing appetite suppression, spontaneous erections, and nausea at higher rates

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