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Delivered via AAV9, a single intracisternal dose enabled sustained brain expression for months and reduced pathological TDP-43 levels in translational mice (Val et al., 2025)

During a six-week induction tracking period, missed meals and low fluid intake more often caused fatigue and lightheadedness than strict calorie targets, so scheduled snacks and hydration reminders resolved symptoms more quickly

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PMID: 29555990

Losing weight can improve ovulation Being overweight or obese can reduce your fertility by causing your menstrual cycles to be irregular or infrequent

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