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Considering the significance of lipid metabolism in ferroptosis and the essential function of lipids in ovarian cancer, stearoyl-coa desaturase (SCD1, SCD) is an enzyme that facilitates the rate-limiting step in the production of monounsaturated fatty acids in ovarian cancer cells

Proc Natl Acad Sci U S A 1997

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Patients were on a stable dose of insulin prior to enrollment with no changes in insulin dose permitted during the run-in period