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Cancer Res 70(12):4949-60, 2010
2 Glutathione deficiencies are common as it can be depleted due to stress, pollutants, aging, and chronic diseases
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Higher levels of 8-hydroxy-2-deoxyguanosine (8-OHdG) were found to be present, which is a marker for oxidative DNA damage, and when melatonin was introduced, there was an appreciable decrease in the levels of 8-OHdG, which shows that melatonin is a protective factor against ROS-induced DNA injuries (189)
J Park Dis 11:949970 Martin A, Youdim K, Szprengiel A, Shukitt-Hale B, Joseph J (2002) Roles of vitamins E and C on neurodegenerative diseases and cognitive performance
Research in obese rodent models has explored its effects on weight gain and fat oxidation, without the broader hormonal actions of full-length growth hormone
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